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1

Quantitative analysis of chromosome conformation capture assays (3C-qPCR)

Hagège, Hélène, Klous, Petra, Braem, Caroline, Splinter, Erik, Dekker, Job, Cathala, Guy, de Laat, Wouter, Forné, Thierry

Journal:

Nature Protocols

Year:

2007

Language:

english

File:

PDF, 254 KB

english, 2007

2

3C-based technologies to study the shape of the genome

Wouter de Laat, Job Dekker

Journal:

Year:

2012

Language:

english

File:

PDF, 357 KB

english, 2012

3

For Genomes to Stay in Shape, Insulators Must Be up to PAR

Wijchers, Patrick J., de Laat, Wouter

Journal:

Year:

2013

Language:

english

File:

PDF, 267 KB

english, 2013

4

Topology of mammalian developmental enhancers and their regulatory landscapes

de Laat, Wouter, Duboule, Denis

Journal:

Year:

2013

Language:

english

File:

PDF, 948 KB

english, 2013

5

A Long-Distance Chromatin Affair

Denker, Annette, de Laat, Wouter

Journal:

Year:

2015

Language:

english

File:

PDF, 226 KB

english, 2015

6

Can We Just Say: Transcription Second?

Krijger, Peter Hugo Lodewijk, de Laat, Wouter

Journal:

Year:

2017

Language:

english

File:

PDF, 268 KB

english, 2017

7

4C-seq from start to end: a detailed protocol for sample preparation and data analysis

Krijger, Peter H.L., Geeven, Geert, Bianchi, Valerio, Hilvering, Catharina R.E., de Laat, Wouter

Journal:

Year:

2019

Language:

english

File:

PDF, 626 KB

english, 2019

8

Hominin-specific regulatory elements selectively emerged in oligodendrocytes and are disrupted in autism patients

Castelijns, Bas, Baak, Mirna L., Timpanaro, Ilia S., Wiggers, Caroline R. M., Vermunt, Marit W., Shang, Peng, Kondova, Ivanela, Geeven, Geert, Bianchi, Valerio, de Laat, Wouter, Geijsen, Niels, Creygh

Journal:

Nature Communications

Year:

2020

Language:

english

File:

PDF, 2.51 MB

english, 2020

9

[IEEE 2019 International Conference on High Performance Computing & Simulation (HPCS) - Dublin, Ireland (2019.7.15-2019.7.19)] 2019 International Conference on High Performance Computing & Simulation (HPCS) - Open Data Market Architecture and Functional Components

Demchenko, Yuri, Cushing, Reggie, Los, Wouter, Grosso, Paola, de Laat, Cees, Gommans, Leon

Year:

2019

File:

PDF, 231 KB

2019

10

Joining the loops: β-Globin gene regulation

Daan Noordermeer, Wouter de Laat

Journal:

Year:

2008

Language:

english

File:

PDF, 299 KB

english, 2008

11

Epidermal growth factor receptor expression during morphological differentiation of pheochromocytoma cells, induced by nerve growth factor or dibutyryl cyclic AMP

Johannes Boonstra, Christine L. Mummery, Alie Feyen, Wouter J. de Hoog, Paul T. van der Saag, Siegfried W. de Laat

Journal:

Journal of Cellular Physiology

Year:

1987

Language:

english

File:

PDF, 1.08 MB

english, 1987

12

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

Guelen, Lars, Pagie, Ludo, Brasset, Emilie, Meuleman, Wouter, Faza, Marius B., Talhout, Wendy, Eussen, Bert H., de Klein, Annelies, Wessels, Lodewyk, de Laat, Wouter

Journal:

Year:

2008

Language:

english

File:

PDF, 1.27 MB

english, 2008

13

The β-globin nuclear compartment in development and erythroid differentiation

Palstra, Robert-Jan, Tolhuis, Bas, Splinter, Erik, Nijmeijer, Rian, Grosveld, Frank, de Laat, Wouter

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.16 MB

english, 2003

14

Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture–on-chip (4C)

Simonis, Marieke, Klous, Petra, Splinter, Erik, Moshkin, Yuri, Willemsen, Rob, de Wit, Elzo, van Steensel, Bas, de Laat, Wouter

Journal:

Nature Genetics

Year:

2006

Language:

english

File:

PDF, 1.48 MB

english, 2006

15

Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes

Skok, Jane A, Gisler, Ramiro, Novatchkova, Maria, Farmer, Deborah, de Laat, Wouter, Busslinger, Meinrad

Journal:

Nature Immunology

Year:

2007

Language:

english

File:

PDF, 533 KB

english, 2007

16

High-resolution identification of balanced and complex chromosomal rearrangements by 4C technology

Simonis, Marieke, Klous, Petra, Homminga, Irene, Galjaard, Robert-Jan, Rijkers, Erik-Jan, Grosveld, Frank, Meijerink, Jules P P, de Laat, Wouter

Journal:

Year:

2009

Language:

english

File:

PDF, 615 KB

english, 2009

17

An evaluation of 3C-based methods to capture DNA interactions

Simonis, Marieke, Kooren, Jurgen, de Laat, Wouter

Journal:

Year:

2007

Language:

english

File:

PDF, 566 KB

english, 2007

18

Studying physical chromatin interactions in plants using Chromosome Conformation Capture (3C)

Louwers, Marieke, Splinter, Erik, van Driel, Roel, de Laat, Wouter, Stam, Maike

Journal:

Nature Protocols

Year:

2009

Language:

english

File:

PDF, 634 KB

english, 2009

19

Nuclear transfer and electrofusion in bovine in vitro-matured/in vitro-fertilized embryos: Effect of media and electrical fusion parameters

Annelies E. P. Van Stekelenburg-Hamers, Wouter G. Van Inzen, Tanja A. E. Van Achterberg, Theo A. M. Kruip, Siegfried W. De Laat, Sjerp M. Weima

Journal:

Molecular Reproduction and Development

Year:

1993

Language:

english

File:

PDF, 729 KB

english, 1993

20

Variegated gene expression caused by cell-specific long-range DNA interactions

Noordermeer, Daan, de Wit, Elzo, Klous, Petra, van de Werken, Harmen, Simonis, Marieke, Lopez-Jones, Melissa, Eussen, Bert, de Klein, Annelies, Singer, Robert H., de Laat, Wouter

Journal:

Nature Cell Biology

Year:

2011

Language:

english

File:

PDF, 4.23 MB

english, 2011

21

The role of receptor protein tyrosine phosphatase α in neuronal differentiation of embryonic stem cells

Wouter G. van Inzen, Maikel P. Peppelenbosch, Maria W.M. van den Brand, Leon G.J. Tertoolen, Siegfried de Laat

Journal:

Developmental Brain Research

Year:

1996

Language:

english

File:

PDF, 291 KB

english, 1996

22

FISH-eyed and genome-wide views on the spatial organisation of gene expression

Marieke Simonis, Wouter de Laat

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2008

Language:

english

File:

PDF, 615 KB

english, 2008

23

Long-range DNA contacts: romance in the nucleus?

Journal:

Current Opinion in Cell Biology

Year:

2007

Language:

english

File:

PDF, 395 KB

english, 2007

24

Genome organization influences partner selection for chromosomal rearrangements

Patrick J. Wijchers, Wouter de Laat

Journal:

Trends in Genetics

Year:

2011

Language:

english

File:

PDF, 401 KB

english, 2011

25

An evolutionarily conserved three-dimensional structure in the vertebrate Irx clusters facilitates enhancer sharing and coregulation

Tena, Juan J., Alonso, M. Eva, de la Calle-Mustienes, Elisa, Splinter, Erik, de Laat, Wouter, Manzanares, Miguel, Gómez-Skarmeta, José Luis

Journal:

Nature Communications

Year:

2011

Language:

english

File:

PDF, 1.19 MB

english, 2011

26

A Regulatory Archipelago Controls Hox Genes Transcription in Digits

Thomas Montavon, Natalia Soshnikova, Bénédicte Mascrez, Elisabeth Joye, Laurie Thevenet, Erik Splinter, Wouter de Laat, François Spitz, Denis Duboule

Journal:

Year:

2011

Language:

english

File:

PDF, 2.01 MB

english, 2011

27

Regulation of phosphoinositide hydrolysis induced by histamine and guanine nucleotides in human HeLa carcinoma cells: Calcium and pH dependence and inhibitory role of protein kinase C

Ben C. Tilly, A.Caro Lambrechts, Leon G.J. Tertoolen, Siegfried W. de Laat, Wouter H. Moolenaar

Journal:

Year:

1990

Language:

english

File:

PDF, 701 KB

english, 1990

28

Nuclear organization revealed by 4C technology

Marieke Simonis, Petra Klous, Erik Splinter, Yuri Moshkin, Rob Willemsen, Elzo de Wit, Bas van Steensel, Wouter de Laat

Journal:

Blood Cells, Molecules, and Diseases

Year:

2007

Language:

english

File:

PDF, 54 KB

english, 2007

29

I/11 cells as a model system to study LCR mediated beta-globin expression

Jurgen Kooren, Robert-Jan Palstra, Erik Splinter, Petra Klous, Frank Grosveld, Wouter de Laat

Journal:

Blood Cells, Molecules, and Diseases

Year:

2007

Language:

english

File:

PDF, 59 KB

english, 2007

30

CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus

Erik Splinter, Helen Heath, Jurgen Kooren, Robert-Jan Palstra, Petra Klous, Frank Grosveld, Niels Galjart, Wouter de Laat

Journal:

Blood Cells, Molecules, and Diseases

Year:

2007

Language:

english

File:

PDF, 61 KB

english, 2007

31

Inter-chromosomal gene regulation in the mammalian cell nucleus

Wouter de Laat, Frank Grosveld

Journal:

Current Opinion in Genetics & Development

Year:

2007

Language:

english

File:

PDF, 1.23 MB

english, 2007

32

Xeroderma Pigmentosum Group F Caused by a Defect in a Structure-Specific DNA Repair Endonuclease

Anneke M Sijbers, Wouter L de Laat, Rafael R Ariza, Maureen Biggerstaff, Ying-Fei Wei, Jonathan G Moggs, Kenneth C Carter, Brenda K Shell, Elizabeth Evans, Mariska C de Jong, Suzanne Rademakers, Johan

Journal:

Year:

1996

Language:

english

File:

PDF, 3.76 MB

english, 1996

33

Looping and Interaction between Hypersensitive Sites in the Active β-globin Locus

Bas Tolhuis, Robert-Jan Palstra, Erik Splinter, Frank Grosveld, Wouter de Laat

Journal:

Year:

2002

Language:

english

File:

PDF, 655 KB

english, 2002

34

Interactions among Polycomb Domains Are Guided by Chromosome Architecture

Tolhuis, Bas, Blom, Marleen, Kerkhoven, Ron M., Pagie, Ludo, Teunissen, Hans, Nieuwland, Marja, Simonis, Marieke, de Laat, Wouter, van Lohuizen, Maarten, van Steensel, Bas, Bickmore, Wendy A.

Journal:

Year:

2011

Language:

english

File:

PDF, 2.04 MB

english, 2011

35

Determining long-range chromatin interactions for selected genomic sites using 4C-seq technology: From fixation to computation

Erik Splinter, Elzo de Wit, Harmen J.G. van de Werken, Petra Klous, Wouter de Laat

Journal:

Year:

2012

Language:

english

File:

PDF, 945 KB

english, 2012

36

eRNAs Are Required for p53-Dependent Enhancer Activity and Gene Transcription

Melo, Carlos A., Drost, Jarno, Wijchers, Patrick J., van de Werken, Harmen, de Wit, Elzo, Vrielink, Joachim A.F. Oude, Elkon, Ran, Melo, Sónia A., Léveillé, Nicolas, Kalluri, Raghu, de Laat, Wouter, A

Journal:

Year:

2013

Language:

english

File:

PDF, 1.31 MB

english, 2013

37

Intracellular ionic compartmentation, electrical membrane properties, and cell membrane permeability before and during first cleavage in the Ambystoma egg

S.W. De Laat, W. Wouters, M.M.Marques Da Silva Pimenta Guarda, M.A. Da Silva Guarda

Journal:

Experimental Cell Research

Year:

1975

Language:

english

File:

PDF, 1.77 MB

english, 1975

38

Rapid effects of nerve growth factor on the Na+,K+-pump in rat pheochromocytoma cells

Johannes Boonstra, Paul T. Van Der Saag, Wouter H. Moolenaar, Siegfried W. De Laat

Journal:

Experimental Cell Research

Year:

1981

Language:

english

File:

PDF, 330 KB

english, 1981

39

Identical cells with different 3D genomes; cause and consequences?

Krijger, Peter HL, de Laat, Wouter

Journal:

Current Opinion in Genetics & Development

Year:

2013

Language:

english

File:

PDF, 413 KB

english, 2013

40

[Current Topics in Developmental Biology] Red Cell Development Volume 82 || Chapter 5 Three‐Dimensional Organization of Gene Expression in Erythroid Cells

de Laat, Wouter

Year:

2008

Language:

english

File:

PDF, 435 KB

english, 2008

41

Maintenance of Long-Range DNA Interactions after Inhibition of Ongoing RNA Polymerase II Transcription

Palstra, Robert-Jan, Simonis, Marieke, Klous, Petra, Brasset, Emilie, Eijkelkamp, Bart, de Laat, Wouter, Tora, Laszlo

Journal:

Year:

2008

Language:

english

File:

PDF, 640 KB

english, 2008

42

Low Accuracy of Tumor Markers for Diagnosing Pancreatic Neuroendocrine Tumors in Multiple Endocrine Neoplasia Type 1 Patients

de Laat, Joanne M., Pieterman, Carolina R. C., Weijmans, Maaike, Hermus, Ad R., Dekkers, Olaf M., de Herder, Wouter W., van der Horst-Schrivers, Anouk N. A., Drent, Madeleine L., Bisschop, Peter H., H

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2013

Language:

english

File:

PDF, 327 KB

english, 2013

43

Long-Range Chromatin Contacts in Embryonic Stem Cells Reveal a Role for Pluripotency Factors and Polycomb Proteins in Genome Organization

Denholtz, Matthew, Bonora, Giancarlo, Chronis, Constantinos, Splinter, Erik, de Laat, Wouter, Ernst, Jason, Pellegrini, Matteo, Plath, Kathrin

Journal:

Year:

2013

Language:

english

File:

PDF, 4.75 MB

english, 2013

44

22-P021 Long-range enhancer–promoter interactions in the HoxD complex

Montavon, Thomas, Mascrez, Bénédicte, Spitz, François, de Laat, Wouter, Duboule, Denis

Journal:

Mechanisms of Development

Year:

2009

Language:

english

File:

PDF, 35 KB

english, 2009

45

Ionic Responses and Growth Stimulation Induced by Nerve Growth Factor and Epidermal Growth Factor in Rat Pheochromocytoma (PC12) Cells

Johannes Boonstra, Wouter H. Moolenaar, Philip H. Harrison, Peter Moed, Paul T. van der Saag and Siegfried W. de Laat

Journal:

The Journal of Cell Biology

Year:

1983

Language:

english

File:

PDF, 1.46 MB

english, 1983

46

Histamine as a Growth Factor and Chemoattractant for Human Carcinoma and Melanoma Cells: Action through Ca2+-Mobilizing H1Receptors

Ben C. Tilly, Leon G. J. Tertoolen, Rolf Remorie, Annie Ladoux, Ingrid Verlaan, Siegfried W. de Laat and Wouter H. Moolenaar

Journal:

The Journal of Cell Biology

Year:

1990

Language:

english

File:

PDF, 268 KB

english, 1990

47

Novel Functional Interactions between Nucleotide Excision DNA Repair Proteins Influencing the Enzymatic Activities of TFIIH, XPG, and ERCC1-XPF †

Winkler, G. Sebastiaan, Sugasawa, Kaoru, Eker, André P. M., de Laat, Wouter L., Hoeijmakers, Jan H. J.

Journal:

Year:

2001

Language:

english

File:

PDF, 125 KB

english, 2001

48

Speech-in-noise screening tests by internet, Part 1: Test evaluation for noise-induced hearing loss identification

Leensen, Monique C. J., de Laat, Jan A. P. M., Dreschler, Wouter A.

Journal:

International Journal of Audiology

Year:

2011

Language:

english

File:

PDF, 421 KB

english, 2011

49

Speech-in-noise screening tests by internet, Part 2: Improving test sensitivity for noise-induced hearing loss

Leensen, Monique C. J., de Laat, Jan A. P. M., Snik, Ad F. M., Dreschler, Wouter A.

Journal:

International Journal of Audiology

Year:

2011

Language:

english

File:

PDF, 477 KB

english, 2011

50

Natural Course and Survival of Neuroendocrine Tumors of Thymus and Lung in MEN1 Patients

de Laat, Joanne M., Pieterman, Carolina R., van den Broek, Medard F., Twisk, Jos W., Hermus, Ad R., Dekkers, Olaf M., de Herder, Wouter W., van der Horst-Schrivers, Anouk N., Drent, Madeleine L., Biss

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2014

Language:

english

File:

PDF, 155 KB

english, 2014